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Na/Bicarbonate Cotransporter NBCn1 in the Kidney Medullary Thick Ascending Limb Cell Line is Upregulated under Acidic Conditions and Enhances Ammonium Transport

In this study, we examined the effect of bicarbonate transporters on ammonium/ammonia uptake in the medullary thick ascending limb cell line ST-1. Cells were treated with 1 mM ouabain and 0.2 mM bumetanide to minimize carrier-mediated NH(4)(+) transport, and the intracellular accumulation of (14)C-m...

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Hlavní autoři: Lee, Soojung, Lee, Hye Jeong, Yang, Han Soo, Thornell, Ian M., Bevensee, Mark O., Choi, Inyeong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923243/
https://ncbi.nlm.nih.gov/pubmed/20591978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2010.053967
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