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Unusual DNA binding modes for metal anticancer complexes
DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis. New platinum drugs can be designed that have novel modes of interaction with DNA, such as the trinuclear platinum complex BBR3464....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923023/ https://ncbi.nlm.nih.gov/pubmed/19344743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2009.03.017 |
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