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Magic Angle Spinning NMR Investigation of Influenza A M2(18-60): Support for an Allosteric Mechanism of Inhibition
[Image: see text] The tetrameric M2 proton channel from influenza A virus conducts protons at low pH and is inhibited by aminoadamantyl drugs such as amantadine and rimantadine. We report magic angle spinning NMR spectra of POPC and DPhPC membrane embedded M2(18-60), both apo and in the presence of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922979/ https://ncbi.nlm.nih.gov/pubmed/20698642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101537p |
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