Transcriptional Suppression of mir-29b-1/mir-29a Promoter by c-Myc, Hedgehog, and NF-kappaB

MicroRNAs regulate pathways contributing to oncogenesis, and thus the mechanisms causing dysregulation of microRNA expression in cancer are of significant interest. Mature mir-29b levels are decreased in malignant cells, and this alteration promotes the malignant phenotype, including apoptosis resis...

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Bibliographic Details
Main Authors: Mott, Justin L., Kurita, Satoshi, Cazanave, Sophie, Bronk, Steven F., Werneburg, Nathan W., Fernandez-Zapico, Martin E.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922950/
https://ncbi.nlm.nih.gov/pubmed/20564213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22630
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