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Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

RASSF7, a member of the N-terminal Ras association domain family, has increased expression in various cancers and, on the basis of our previous work in Xenopus embryos, may be a regulator of mitosis. In the present study, we address, for the first time, the role of human RASSF7 in mitosis. We demons...

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Autors principals: Recino, Asha, Sherwood, Victoria, Flaxman, Amy, Cooper, Wendy N., Latif, Farida, Ward, Andrew, Chalmers, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922839/
https://ncbi.nlm.nih.gov/pubmed/20629633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100883
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