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Genome-wide Identification of PAX3-FKHR Binding Sites in Rhabdomyosarcoma Reveals Candidate Target Genes Important for Development and Cancer

The PAX3-FKHR fusion protein is present in the majority of alveolar rhabdomyosarcoma (ARMS) associated with increased aggressiveness and poor prognosis. To better understand the molecular pathogenesis of PAX3-FKHR, we carried out the first and unbiased genome-wide identification of PAX3-FKHR binding...

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Detalhes bibliográficos
Main Authors: Cao, Liang, Yu, Yunkai, Bilke, Sven, Walker, Robert L., Mayeenuddin, Linnia H., Azorsa, David O., Yang, Fan, Pineda, Marbin, Helman, Lee J., Meltzer, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922412/
https://ncbi.nlm.nih.gov/pubmed/20663909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0582
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