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Hepatic Gene Expression Profiling Reveals Key Pathways Involved in Leptin-Mediated Weight Loss in ob/ob Mice

BACKGROUND: Leptin, a cytokine-like protein, plays an important role in the regulation of body weight through inhibition of food intake and stimulation of energy expenditure. Leptin circulates in blood and acts on the brain, which sends downstream signals to regulate body weight. Leptin therapy has...

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Detalhes bibliográficos
Main Authors: Sharma, Ashok, Bartell, Shoshana M., Baile, Clifton A., Chen, Bo, Podolsky, Robert H., McIndoe, Richard A., She, Jin-Xiong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922341/
https://ncbi.nlm.nih.gov/pubmed/20808936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012147
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