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Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase

DNA replication requires priming of DNA templates by enzymes known as primases. Although DNA primase structures are available from archaea and bacteria, the mechanism of DNA priming in higher eukaryotes remains poorly understood in large part due to the absence of the structure of the unique, highly...

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Autori principali: Vaithiyalingam, Sivaraja, Warren, Eric M., Eichman, Brandt F., Chazin, Walter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922289/
https://ncbi.nlm.nih.gov/pubmed/20643958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002009107
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