Alterations in the immuno-skeletal interface drive bone destruction in HIV-1 transgenic rats

Osteoporosis and bone fractures are increasingly recognized complications of HIV-1 infection. Although antiretroviral therapy itself has complex effects on bone turnover, it is now evident that the majority of HIV-infected individuals already exhibit reduced bone mineral density before therapy. The...

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Main Authors: Vikulina, Tatyana, Fan, Xian, Yamaguchi, Masayoshi, Roser-Page, Susanne, Zayzafoon, Majd, Guidot, David M., Ofotokun, Ighovwerha, Weitzmann, M. Neale
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922243/
https://ncbi.nlm.nih.gov/pubmed/20643942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003020107
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