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Extremely slow intramolecular diffusion in unfolded protein L

A crucial parameter in many theories of protein folding is the rate of diffusion over the energy landscape. Using a microfluidic mixer we have observed the rate of intramolecular diffusion within the unfolded B1 domain of protein L before it folds. The diffusion-limited rate of intramolecular contac...

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Bibliografske podrobnosti
Main Authors: Waldauer, Steven A., Bakajin, Olgica, Lapidus, Lisa J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922234/
https://ncbi.nlm.nih.gov/pubmed/20643973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005415107
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