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High-throughput engineering and analysis of peptide binding to class II MHC

Class II major histocompatibility complex (MHC-II) proteins govern stimulation of adaptive immunity by presenting antigenic peptides to CD4+ T lymphocytes. Many allelic variants of MHC-II exist with implications in peptide presentation and immunity; thus, high-throughput experimental tools for rapid...

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Detalhes bibliográficos
Main Authors: Jiang, Wei, Boder, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922119/
https://ncbi.nlm.nih.gov/pubmed/20622157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006344107
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