The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats

BACKGROUND: Activation of glucagon-like peptide-1 (GLP-1) receptors improves insulin sensitivity and induces vasodilatation and diuresis. AC3174 is a peptide analogue with pharmacologic properties similar to the GLP-1 receptor agonist, exenatide. Hypothetically, chronic AC3174 treatment could attenu...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Que, Adams, Lisa, Broyde, Anatoly, Fernandez, Rayne, Baron, Alain D, Parkes, David G
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Original Investigation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922097/
https://ncbi.nlm.nih.gov/pubmed/20678234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-32
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