Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure

BACKGROUND: Accumulating evidence suggests glucagon-like peptide-1 (GLP-1) exerts cardioprotective effects in animal models of myocardial infarction (MI). We hypothesized that chronic treatment with GLP-1 or the exenatide analog AC3174 would improve cardiac function, cardiac remodeling, insulin sens...

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Main Authors: Liu, Que, Anderson, Christen, Broyde, Anatoly, Polizzi, Clara, Fernandez, Rayne, Baron, Alain, Parkes, David G
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996354/
https://ncbi.nlm.nih.gov/pubmed/21080957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-76
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