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Targeting Adenoviruses with Factor X–Single-Chain Antibody Fusion Proteins
It has been shown that blood clotting factors, including factor X (FX), bind to the adenovirus serotype 5 (Ad5) hexon protein and target the virus to liver hepatocytes after intravenous injection. These factors bind to hexon via their conserved vitamin K-dependent γ-carboxyglutamic acid (GLA) domain...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922071/ https://ncbi.nlm.nih.gov/pubmed/20331369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.190 |
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