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Inhibition of Endothelin-1 Receptors Improves Impaired Nitric Oxide Synthase-Dependent Dilation of Cerebral Arterioles in Type 1 Diabetic Rats

OBJECTIVE: Endothelin-1 has been implicated in the pathogenesis of many cardiovascular-related diseases, including diabetes. The goal of this study was to examine the influence of endothelin-1 receptors (ET(A)) in impaired responses of cerebral (pial) arterioles in Type 1 diabetic rats. METHODS: We...

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Detalhes bibliográficos
Main Authors: Arrick, Denise M., Mayhan, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922043/
https://ncbi.nlm.nih.gov/pubmed/20690982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1549-8719.2010.00042.x
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