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Losartan Improves Impaired Nitric Oxide Synthase-Dependent Dilatation of Cerebral Arterioles in Type 1 Diabetic Rats

We examined whether activation of angiotensin-1 receptors (AT1R) could account for impaired responses of cerebral arterioles during Type 1 diabetes (T1D). First, we measured responses of cerebral arterioles in nondiabetic rats to eNOS-dependent (acetylcholine and adenosine diphosphate (ADP)) and -in...

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Detalhes bibliográficos
Main Authors: Arrick, Denise M., Sharpe, Glenda M., Sun, Hong, Mayhan, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705945/
https://ncbi.nlm.nih.gov/pubmed/18400212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.03.020
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