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Beta-lactam antibiotic reduces morphine analgesic tolerance in rats through GLT-1 transporter activation
Glutamate transporter subtype 1 (GLT-1) activation is a promising – and understudied - approach for managing aspects of morphine tolerance caused by increased glutamatergic transmission. Identification of beta-lactam antibiotics as pharmaceuticals which activate GLT-1 transporters prompted us to hyp...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921944/ https://ncbi.nlm.nih.gov/pubmed/20004063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2009.10.010 |
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