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Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range

Spreading depression (SD) is a slowly propagating wave of transient neuronal and glial depolarization that develops after stroke, trauma and subarachnoid hemorrhage. In compromised tissue, repetitive SD-like injury depolarizations reduce tissue viability by worsening the mismatch between blood flow...

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Detalhes bibliográficos
Main Authors: Sukhotinsky, Inna, Yaseen, Mohammad A, Sakadžić, Sava, Ruvinskaya, Svetlana, Sims, John R, Boas, David A, Moskowitz, Michael A, Ayata, Cenk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921789/
https://ncbi.nlm.nih.gov/pubmed/20087371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.285
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