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Cortical spreading depression impairs oxygen delivery and metabolism in mice
Cortical spreading depression (CSD) is associated with severe hypoperfusion in mice. Using minimally invasive multimodal optical imaging, we show that severe flow reductions during and after spreading depression are associated with a steep decline in cerebral metabolic rate of oxygen. Concurrent sev...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272607/ https://ncbi.nlm.nih.gov/pubmed/22008729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.148 |
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