Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

Age-related macular degeneration (AMD) is the most common form of irreversible blindness in developed countries1,2. Variants in the factor H gene (CFH, also known as HF1), which encodes a major inhibitor of the alternative complement pathway, are associated with the risk for developing AMD3–8. Here...

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Autors principals: Gold, Bert, Merriam, Joanna E, Zernant, Jana, Hancox, Lisa S, Taiber, Andrew J, Gehrs, Karen, Cramer, Kevin, Neel, Julia, Bergeron, Julie, Barile, Gaetano R, Smith, R Theodore, Hageman, Gregory S, Dean, Michael, Allikmets, Rando
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921703/
https://ncbi.nlm.nih.gov/pubmed/16518403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1750
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