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The power of the Transmission Disequilibrium Test in the presence of population stratification

The Transmission Disequilibrium Test (TDT) is a family-based test for association based on the rate of transmission of alleles from heterozygous parents to affected offspring, and has gained popularity as this test preserves the Type I error rate. Population stratification results in a decreased num...

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Detalhes bibliográficos
Main Authors: Sebro, Ronnie, Rogus, John J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921480/
https://ncbi.nlm.nih.gov/pubmed/20442746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.57
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