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RECOMBINANT FORM OF HUMAN WILD TYPE MANNAN-BINDING LECTIN (MBL/A) BUT NOT ITS STRUCTURAL VARIANT (MBL/C) PROMOTES PHAGOCYTOSIS OF ZYMOSAN BY ACTIVATING COMPLEMENT
Mannan-binding lectin (MBL) mediates innate immune responses, such as activation of the complement lectin pathway and phagocytosis, to help fight infections. In the present study, employing recombinant forms of human MBL (rMBL), the role of wild type MBL (rMBL/A) and its structural variant rMBL/C in...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921464/ https://ncbi.nlm.nih.gov/pubmed/20579738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.05.292 |
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