RECOMBINANT FORM OF HUMAN WILD TYPE MANNAN-BINDING LECTIN (MBL/A) BUT NOT ITS STRUCTURAL VARIANT (MBL/C) PROMOTES PHAGOCYTOSIS OF ZYMOSAN BY ACTIVATING COMPLEMENT

Mannan-binding lectin (MBL) mediates innate immune responses, such as activation of the complement lectin pathway and phagocytosis, to help fight infections. In the present study, employing recombinant forms of human MBL (rMBL), the role of wild type MBL (rMBL/A) and its structural variant rMBL/C in...

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Hlavní autoři: Rajagopalan, Rema, Nyaundi, Takazvida, Salvi, Veena P., Rawal, Nenoo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921464/
https://ncbi.nlm.nih.gov/pubmed/20579738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.05.292
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