Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes

The lectin pathway (LP) of complement activation depends on the activation of the MBL-associated serine proteases (MASPs) circulating in complex with mannan-binding lectin (MBL). MBL deficiency is the most common complement deficiency and has been associated with several pathological conditions. As...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Keizer, Mischa P., Kamp, Angela, van Mierlo, Gerard, Kuijpers, Taco W., Wouters, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030254/
https://ncbi.nlm.nih.gov/pubmed/29997613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01406
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