Endoplasmic reticulum stress response in an INS-1 pancreatic β-cell line with inducible expression of a folding-deficient proinsulin

BACKGROUND: Cells respond to endoplasmic reticulum stress (ER) stress by activating the unfolded protein response. To study the ER stress response in pancreatic β-cells we developed a model system that allows for pathophysiological ER stress based on the Akita mouse. This mouse strain expresses a mu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hartley, Taila, Siva, Madura, Lai, Elida, Teodoro, Tracy, Zhang, Liling, Volchuk, Allen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921384/
https://ncbi.nlm.nih.gov/pubmed/20659334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-11-59
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