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Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid

BACKGROUND: Alzheimer's disease (AD) and cerebrovascular disease (CVD) including chronic small vessel disease of the brain (SVD) are the most frequent causes of dementia. AD is associated with metabolism of amyloid precursor protein (APP) and low levels of amyloid-β peptide (Aβ) X-42 in the cer...

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Autori principali: Selnes, Per, Blennow, Kaj, Zetterberg, Henrik, Grambaite, Ramune, Rosengren, Lars, Johnsen, Lisbeth, Stenset, Vidar, Fladby, Tormod
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921347/
https://ncbi.nlm.nih.gov/pubmed/20673341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8454-7-10
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