Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid

BACKGROUND: Alzheimer's disease (AD) and cerebrovascular disease (CVD) including chronic small vessel disease of the brain (SVD) are the most frequent causes of dementia. AD is associated with metabolism of amyloid precursor protein (APP) and low levels of amyloid-β peptide (Aβ) X-42 in the cer...

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Detalhes bibliográficos
Main Authors: Selnes, Per, Blennow, Kaj, Zetterberg, Henrik, Grambaite, Ramune, Rosengren, Lars, Johnsen, Lisbeth, Stenset, Vidar, Fladby, Tormod
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921347/
https://ncbi.nlm.nih.gov/pubmed/20673341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8454-7-10
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