Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid

BACKGROUND: Alzheimer's disease (AD) and cerebrovascular disease (CVD) including chronic small vessel disease of the brain (SVD) are the most frequent causes of dementia. AD is associated with metabolism of amyloid precursor protein (APP) and low levels of amyloid-β peptide (Aβ) X-42 in the cer...

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Hlavní autoři: Selnes, Per, Blennow, Kaj, Zetterberg, Henrik, Grambaite, Ramune, Rosengren, Lars, Johnsen, Lisbeth, Stenset, Vidar, Fladby, Tormod
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921347/
https://ncbi.nlm.nih.gov/pubmed/20673341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8454-7-10
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