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n→π* Interactions in Proteins

Hydrogen bonds between backbone amides are common in folded proteins. Here, we show that an intimate interaction between backbone amides likewise arises from the delocalization of a lone pair of electrons (n) from an oxygen atom to the antibonding orbital (π*) of the subsequent carbonyl group. Natur...

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Bibliografiske detaljer
Main Authors: Bartlett, Gail J., Choudhary, Amit, Raines, Ronald T., Woolfson, Derek N.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921280/
https://ncbi.nlm.nih.gov/pubmed/20622857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.406
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