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PHARMACOLOGICAL PROPERTIES OF ORALLY AVAILABLE, AMPHIPATHIC POLYAMINOCARBOXYLIC ACID CHELATORS FOR ACTINIDE DECORPORATION
Commonly used water-soluble polyaminocarboxylic acid (PACA) chelators, such as (EDTA) and DTPA, require intravenous or subcutaneous administration due to their poor bioavailability. The bioavailability of PACAs can be improved by the addition of differing lengths of alkyl side chains that alter amph...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921225/ https://ncbi.nlm.nih.gov/pubmed/20699705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HP.0b013e3181bfb99b |
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