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A Trim5alpha Exon 2 Polymorphism is Associated with Protection from HIV-1 Infection in Pumwani Sexworker Cohort

OBJECTIVE: The innate immune component TRIM5α has the ability to restrict retrovirus infection in a species-specific manner. TRIM5α of some primate species restricts infection by HIV-1, while huTRIM5α lacks this specificity. Previous studies have suggested that certain polymorphisms in huTRIM5 may e...

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Detalhes bibliográficos
Principais autores: Price, Heather, Lacap, Philip, Tuff, Jeff, Wachihi, Charles, Kimani, Joshua, Ball, Terry B., Luo, Ma, Plummer, Francis A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921035/
https://ncbi.nlm.nih.gov/pubmed/20588169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32833b5256
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