Direct measurement of proinsulin in human plasma by the use of an insulin-degrading enzyme

A method has been described for the direct measurement of proinsulin in human plasma. The method makes use of an insulin-degrading enzyme designated “insulin-specific protease (ISP)”, which is obtained from rat skeletal muscle. Under the conditions used, this enzyme rapidly degrades insulin and insu...

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Pubblicato in:	J Clin Invest
Autori principali:	Kitabchi, Abbas E., Duckworth, William C., Brush, James S., Heinemann, Martha
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1971
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292103/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4327576/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106669
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