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Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them

Recent reports of strong selection of mitochondrial DNA (mtDNA) during transmission in animal models of mtDNA disease, and of nuclear transfer in both animal models and humans, have important scientific implications. These are directly applicable to the genetic management of mtDNA disease. The risk...

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Détails bibliographiques
Auteurs principaux: Poulton, Joanna, Chiaratti, Marcos R., Meirelles, Flávio V., Kennedy, Stephen, Wells, Dagan, Holt, Ian J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920841/
https://ncbi.nlm.nih.gov/pubmed/20711358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001066
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