Puma and Trail/Dr5 Pathways Control Radiation-Induced Apoptosis in Distinct Populations of Testicular Progenitors

Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after γ-irradiation but the death effectors are still poorly characterized. Our data demonstrate that both intrinsic and extrinsic apoptotic pathways are involved, and especially...

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Main Authors: Coureuil, Mathieu, Ugolin, Nicolas, Tavernier, Marie, Chevillard, Sylvie, Barroca, Vilma, Fouchet, Pierre, Allemand, Isabelle
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920820/
https://ncbi.nlm.nih.gov/pubmed/20711434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012134
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