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Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation
Bone marrow injury is a major adverse side effect of radiation and chemotherapy. Attempts to limit such damage are warranted, but their success requires a better understanding of how radiation and anticancer drugs harm the bone marrow. Here, we report one pivotal role of the BH3-only protein Puma in...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890171/ https://ncbi.nlm.nih.gov/pubmed/20360471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-248872 |
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