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Fra-2 mediates oxygen-sensitive induction of transforming growth factor β in cardiac fibroblasts
AIMS: In the ischaemia-reperfused heart, transforming growth factor β (TGFβ) proteins trigger the differentiation of cardiac fibroblasts (CFs) contributing to fibrosis. Reoxygenation of the heart, in addition to being a trigger for reperfusion injury, induces tissue remodelling by hyperoxia-sensitiv...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920807/ https://ncbi.nlm.nih.gov/pubmed/20427335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq123 |
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