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Nrf2 and Keap1 Abnormalities in Non-Small Cell Lung Carcinoma and Association with Clinicopathologic Features

PURPOSE: To understand the role of Nrf2 and Keap1 in NSCLC, we studied their expression in a large series of tumors with annotated clinicopathologic data, including response to platinum-based adjuvant chemotherapy. EXPERIMENTAL DESIGN: We determined the immunohistochemical expression of nuclear Nrf2...

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Detalhes bibliográficos
Main Authors: Solis, Luisa M., Behrens, Carmen, Dong, Wenli, Suraokar, Milind, Ozburn, Natalie C., Moran, Cesar A., Corvalan, Alejandro H., Biswal, Shyam, Swisher, Stephen G., Bekele, B. Nebiyou, Minna, John D., Stewart, David J., Wistuba, Ignacio I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920733/
https://ncbi.nlm.nih.gov/pubmed/20534738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-3352
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