Architecture-Dependent Robustness and Bistability in a Class of Genetic Circuits

Understanding the relationship between genotype and phenotype is a challenge in systems biology. An interesting yet related issue is why a particular circuit topology is present in a cell when the same function can supposedly be obtained from an alternative architecture. Here we analyzed two topolog...

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Bibliographic Details
Main Authors: Zhang, Jiajun, Yuan, Zhanjiang, Li, Han-Xiong, Zhou, Tianshou
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Biological Systems and Multicellular Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920723/
https://ncbi.nlm.nih.gov/pubmed/20712986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.036
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