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Down-regulation of E-cadherin is an essential event in activating β-catenin/Tcf dependent transcription and expression of its target genes in Pdcd4 knock-down cells
We previously reported that knock-down of tumor suppressor Pdcd4 (Programmed Cell Death 4) down-regulates E-cadherin expression and activates β-catenin/Tcf (T cell factor) dependent transcription in colon tumor cells. However, the underlying mechanism of these observations remains unknown. In this s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920641/ https://ncbi.nlm.nih.gov/pubmed/19784072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.302 |
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