Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

The trimeric Sec61/SecY complex is a protein-conducting channel (PCC) for secretory and membrane proteins. Although Sec complexes can form oligomers, it has been suggested that a single copy may serve as an active PCC. We determined sub-nanometer resolution cryo-electron microscopy structures of euk...

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Autores principales: Becker, Thomas, Bhushan, Shashi, Jarasch, Alexander, Armache, Jean-Paul, Funes, Soledad, Jossinet, Fabrice, Gumbart, James, Mielke, Thorsten, Berninghausen, Otto, Schulten, Klaus, Westhof, Eric, Gilmore, Reid, Mandon, Elisabet, Beckmann, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920595/
https://ncbi.nlm.nih.gov/pubmed/19933108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178535
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