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The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency

RNA silencing is a complex of mechanisms that regulate gene expression through small RNA molecules. The microRNA (miRNA) pathway is the most common of these in mammals. Genome-encoded miRNAs suppress translation in a sequence-specific manner and facilitate shifts in gene expression during developmen...

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Bibliografiske detaljer
Main Authors: Svoboda, Petr, Flemr, Matyas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920432/
https://ncbi.nlm.nih.gov/pubmed/20651740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.102
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