Metabolic Preconditioning of Cells with AICAR-Riboside: Improved Cryopreservation and Cell-Type Specific Impacts on Energetics and Proliferation

In species whose evolutionary history has provided natural tolerance to dehydration and freezing, metabolic depression is often a pre-requisite for survival. We tested the hypothesis that preconditioning of mammalian cells with 5-aminoimidazole-4-carboxamide-1-b-D-ribofuranoside (AICAR) to achieve m...

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Hauptverfasser: Menze, Michael A., Chakraborty, Nilay, Clavenna, Matthew, Banerjee, Mitali, Liu, Xiang-Hong, Toner, Mehmet, Hand, Steven C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920351/
https://ncbi.nlm.nih.gov/pubmed/20510224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cryobiol.2010.05.004
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