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Epitope mapping in cell surface proteins by site-directed masking: defining the structural elements of NTPDase3 inhibition by a monoclonal antibody
We adapted the method of epitope mapping by site-directed masking, which was described for purified soluble antigens [Paus,D. and Winter,G. (2006) Proc. Natl Acad. Sci. USA, 103, 9172–9177.], to map the binding site of an inhibitory monoclonal antibody on the cell surface protein ecto-nucleotidase N...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920303/ https://ncbi.nlm.nih.gov/pubmed/20511214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq027 |
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