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Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice

OBJECTIVES: The antischistosomal properties of the marketed antiandrogens bicalutamide, flutamide, nilutamide and cyproterone acetate were studied both in vivo and in vitro. METHODS: Schistosoma mansoni-infected mice were treated orally with 50–400 mg/kg of the antiandrogens 3 and 7 weeks post-infec...

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Bibliografiske detaljer
Main Authors: Keiser, Jennifer, Vargas, Mireille, Vennerstrom, Jonathan L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920177/
https://ncbi.nlm.nih.gov/pubmed/20576641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq233
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