Cyclic 3′,5′-adenosine monophosphate in the human leukocyte: synthesis, degradation, and effects on neutrophil candidacidal activity

Prostaglandins E(1) and E(2) (PGE(1) and PGE(2)) stimulate adenyl cyclase activity in broken cell preparations of normal human leukocytes, whereas prostaglandin F(1a) produces no effect. PGE(1) and PGE(2) also cause increased accumulation of cyclic 3′,5′-adenosine monophosphate-(3)H ((3)H-labeled AM...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Bourne, Henry R., Lehrer, Robert I., Cline, Martin J., Melmon, Kenneth L.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1971
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292007/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106564
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