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Cyclic 3′,5′-adenosine monophosphate in the human leukocyte: synthesis, degradation, and effects on neutrophil candidacidal activity

Prostaglandins E(1) and E(2) (PGE(1) and PGE(2)) stimulate adenyl cyclase activity in broken cell preparations of normal human leukocytes, whereas prostaglandin F(1a) produces no effect. PGE(1) and PGE(2) also cause increased accumulation of cyclic 3′,5′-adenosine monophosphate-(3)H ((3)H-labeled AM...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bourne, Henry R., Lehrer, Robert I., Cline, Martin J., Melmon, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106564
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