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AMPKα2 deletion Causes Aberrant Expression and Activation of NAD(P)H Oxidase and Consequent Endothelial Dysfunction in vivo: Role of 26S Proteasomes

RATIONAL: AMP-activated protein kinase (AMPK) is an energy sensor and ubiquitously expressed in vascular cells. Recent studies suggest that AMPK activation improves endothelial function by counteracting oxidative stress in endothelial cells. How AMPK suppresses oxidative stress remains to be establi...

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Detalhes bibliográficos
Main Authors: Wang, Shuangxi, Zhang, Miao, Liang, Bin, Xu, Jian, Xie, Zhonglin, Liu, Chao, Viollet, Benoit, Yan, Daoguang, Zou, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920052/
https://ncbi.nlm.nih.gov/pubmed/20167927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.212530
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