Circulating insulin: the proinsulin-like properties of “big” insulin in patients without islet cell tumors

When plasma is filtered on Sephadex G-50, insulin immunoreactivity is recovered in two peaks. “Big” insulin, the higher molecular weight component, and “little” insulin, the lower molecular weight component, have elution volumes that correspond to those of proinsulin-(125)I and insulin-(125)I respec...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Sherman, Barry M., Gorden, Phillip, Roth, Jesse, Freychet, Pierre
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1971
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4323127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106556
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