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Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

The reprogramming of fibroblasts to induced pluripotent stem (iPS) cells raises the possibility that a somatic cell could be reprogrammed to an alternative differentiated fate without first becoming a stem/progenitor cell. A large pool of fibroblasts exists in the post-natal heart, yet no single “ma...

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Hlavní autoři: Ieda, Masaki, Fu, Ji-Dong, Delgado-Olguin, Paul, Vedantham, Vasanth, Hayashi, Yohei, Bruneau, Benoit G., Srivastava, Deepak
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919844/
https://ncbi.nlm.nih.gov/pubmed/20691899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.07.002
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