Ultrafast and high-throughput mass spectrometric assay for therapeutic drug monitoring of antiretroviral drugs in pediatric HIV-1 infection applying dried blood spots

Kaletra® (Abott Laboratories) is a co-formulated medication used in the treatment of HIV-1-infected children, and it contains the two antiretroviral protease inhibitor drugs lopinavir and ritonavir. We validated two new ultrafast and high-throughput mass spectrometric assays to be used for therapeut...

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Hauptverfasser: Meesters, Roland J. W., van Kampen, Jeroen J. A., Reedijk, Mariska L., Scheuer, Rachel D., Dekker, Lennard J. M., Burger, David M., Hartwig, Nico G., Osterhaus, Albert D. M. E., Luider, Theo M., Gruters, Rob A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919689/
https://ncbi.nlm.nih.gov/pubmed/20632164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-3952-9
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