Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate—a validated assay for the clinic

The neuraminidase inhibitor oseltamivir (Tamiflu®) is currently the first-line therapy for patients with influenza virus infection. Common analysis of the prodrug and its active metabolite oseltamivircarboxylate is determined via extraction from plasma. Compared with these assays, dried blood spot (...

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Main Authors: Hooff, Gero P., Meesters, Roland J. W., van Kampen, Jeroen J. A., van Huizen, Nick A., Koch, Birgit, Al Hadithy, Asmar F. Y., van Gelder, Teun, Osterhaus, Albert D. M. E., Gruters, Rob A., Luider, Theo M.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2011
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Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119796/
https://ncbi.nlm.nih.gov/pubmed/21537911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-5050-z
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