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Inhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid balance and spatial memory in mice

The sphingolipid ceramide is a bioactive signaling lipid that is thought to play important roles in modulating synaptic activity, in part by regulating the function of excitatory postsynaptic receptors. However, the molecular mechanisms by which ceramide exerts its effects on synaptic activity remai...

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Detalhes bibliográficos
Main Authors: Tabatadze, Nino, Savonenko, Alena, Song, Hongjun, Bandaru, Veera Venkata Ratnam, Chu, Michael, Haughey, Norman J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919585/
https://ncbi.nlm.nih.gov/pubmed/20629193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22438
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